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Opportunities for student training in laboratory research in Molecular Medicine and Genetics are available as part of the Center for Molecular Medicine and Genetics SURP. Areas of study include, the molecular biology of cancer, chromosome structure and function, gene regulation, molecular neurobiology, differentiation and development, genetic engineering and molecular evolution.
Below are the research interests of CMMG faculty participating in SURP 2007:
Leon Carlock,
Molecular neurobiology; Huntington’s disease;
neuron-specific gene expression; demyelinating disease.
Gerald
Feldman, Use of molecular technologies in the
diagnosis of genetic diseases; clinical genetics and
dysmorphology; al programs in medical genetics
residency training.
Russell L. Finley, Jr.
Regulatory networks that control cell proliferation; cell
cycle regulation during development; yeast technology.
James Y. Garbern,
Neurogenetics; molecular biology of meiotic disorders;
molecular pathogenesis of glial tumors; homeobox genes.
Craig N. Giroux,
Functional genomics of gene-environment interactions;
genetic toxicology and pharmacogenetics; genome stability
and meiotic differentiation; cellular biosensors and
biotechnology.
Morris Goodman,
Molecular evolution, with emphasis on globin genes and
primate phylogeny.
Alexander
Gow, Molecular pathogenesis of CNS diseases;
molecular characterization of the claudin family of integral
membrane tight junction proteins during development in
brain, testes and inner ear using transgenic and homologous
recombination in embryonic stem cells.
Anne E.
Greb, al programs in human genetics
and genetics counseling; multicultural issues related to
genetic counseling and the provision of clinical genetics
services.
Lawrence I. Grossman,
Molecular genetics and evolution of the electron transport
chain; cytochrome c oxidase; mitochondria and
mitochondrial diseases.
Henry H.Q. Heng,
Molecular cytogenetics; high order structure of chromosomes;
genome structure and function; genetic and physical mapping;
genomic instability and cancer.
Maik Hüttemann, Function of cytochrome c oxidase
isoforms, oxygen sensing, and role of mitochondria in
cancer.
John Kamholz,
Regulation of myelination; molecular pathophysiology of
demyelinating disease.
Greg
Kapatos, Cellular and molecular biology of
monoamine neurotransmitter secreting neurons.
Stephen A.
Krawetz, Gene therapy; control of development
and differentiation; expression of connective tissue genes
and genes controlling spermatogenesis; computer-assisted
sequence analysis.
S. Helena Kuivaniemi,
Molecular biology and genetics of aortic aneurysms.
Markku Kurkinen,
Extracellular matrix; metalloproteinases; gene regulation;
development; disease.
Wayne Lancaster,
Papillomaviruses: molecular biology, evolution, and role in
human carcinogenesis; cancer cell genome instability;
ovarian carcinogenesis.
Susan
Land, Genomics.
Li Li, Gene
regulation during cardiovascular and hematopoietic
development.
Jeffrey Loeb,
Developmental neuroscience; molecular mechanisms in synapse
formation; neuregulins and neurotrophins in synaptic
development; functional genomic study of the pathogenesis of
epilepsy.
Michael E.
Shy, Molecular biology of Schwann cell axonal
interactions; gene therapy in the peripheral nervous system.
Michael Tainsky,
Inherited cancer and genomic instability; control of
transcription in cancer cells; Li-Fraumeni familial cancer
syndrome.
Angela Trepanier, al programs in human genetics
and genetic counseling; cancer genetics.
Gerard Tromp,
Genetic epidemiology and linkage analysis; molecular biology
and genetics of intracranial aneurysms; the Blau syndrome;
bioinformatics and genomics.
David D.
Womble, Bioinformatics, Control of DNA
replication and segregation; regulation of the cell division
cycle. |
