I am interested in systems-wide characterization of epilepsy-related diseases from molecular, histological and electrophysiological perspectives. My research focuses on a structural brain malformation, polymicrogyria (PMG). More than 70% of patients with PMG also present with epilepsy, often necessitating surgical intervention. These surgically resected tissues are the basis of my studies.
Merrell KW, Crofts JD, Smith RL, Sin JH, Kmetzsch KE, Merrell A, Miguel RO, Candelaria NR, Lin CY. Differential recruitment of nuclear receptor coregulators in ligand-dependent transcriptional repression by estrogen receptor-a. Oncogene. 2011 Mar 31;30(13): 1608-14.