Leon R. Carlock, PhD

Leon R. Carlock, PhD
Associate Professor of Molecular Medicine and Genetics and of Anatomy and Cell Biology
Lande Building, Rm 452
550 E. Canfield Avenue
Detroit, MI 48201


Purdue University, PhD, 1981

Research Focus

Molecular neurobiology; Huntington's disease; neuron-specific gene expression; demyelinating disease

Recent Publications

Boucher SE, Cypher MA, Carlock LR, Skoff RP. Proteolipid protein gene modulates viability and phenotype of neurons. J Neurosci. 2002 Mar 1;22(5):1772-83. PubMed PMID: 11880506.

Fusco FR, Chen Q, Lamoreaux WJ, Figueredo-Cardenas G, Jiao Y, Coffman JA, Surmeier DJ, Honig MG, Carlock LR, Reiner A. Cellular localization of huntingtin in striatal and cortical neurons in rats: lack of correlation with neuronal vulnerability in Huntington's disease. J Neurosci. 1999 Feb 15;19(4):1189-202. PubMed PMID: 9952397.

Moore PM, Vo T, Carlock LR. Identification and cloning of a brain autoantigen in neuro-behavioral SLE. J Neuroimmunol. 1998 Mar 1;82(2):116-25. PubMed PMID: 9585807.

Shan Y, Carlock LR, Walker PD. NMDA receptor overstimulation triggers a prolonged wave of immediate early gene expression: relationship to excitotoxicity. Exp Neurol. 1997 Apr;144(2):406-15. PubMed PMID: 9168840.

Walker PD, Capodilupo JG, Wolf WA, Carlock LR. Preprotachykinin and preproenkephalin mRNA expression within striatal subregions in response to altered serotonin transmission. Brain Res. 1996 Sep 2;732(1-2):25-35. PubMed PMID: 8891265.

Bessert DA, Gutridge KL, Dunbar JC, Carlock LR. The identification of a functional nuclear localization signal in the Huntington disease protein. Brain Res Mol Brain Res. 1995 Oct;33(1):165-73. PubMed PMID: 8774958.

Walker PD, Carlock LR. Immediate early gene activation during the initial phases of the excitotoxic cascade. J Neurosci Res. 1993 Dec 1;36(5):588-95. PubMed PMID: 8145290.