Basic Neuroscience Publications:
Li Q, Loeb JA (2001) Neuregulin-HSPG interactions produce sustained ErbB receptor activation required for the induction of AChRs in muscle. J Biol. Chem. 276:38068-38075.Loeb JA, Hmadcha
A,
Fischbach GD, Land SJ, and Zakarian VL (2002) Neuregulin Expression at
Neuromuscular Synapses is Modulated by Synaptic Activity and
Neurotrophic
Factors,
J. Neurosci. 22:2206-2214.
Loeb JA (2003) Neuregulin:
An Activity-Dependent Synaptic Modulator at the Neuromuscular Junction.
J
Neurocytol. 32:649-664.
Li
Q, Esper RM, and Loeb JA (2004) Synergistic
Effects of Neuregulin and Agrin on Muscle Acetylcholine Receptor
Expression.
Mol. Cell. Neurosci. 26:558-69.
Esper
RM and Loeb JA (2004) Rapid
axoglial signaling mediated by neuregulin and neurotrophic factors. J. Neurosci. 24:6218-27.
Yao
B, Rakhade SN, Li Q, Ahmed A, Krauss R, Draghici S, and Loeb JA (2004) Accuracy
of cDNA microarray methods to detect small gene expression changes
induced by
neuregulin on breast epithelial cells BMC Bioinformatics 2004, 5:99
Li
Q, Ahmed S, and Loeb JA (2004) Development
of a proliferative autocrine neuregulin signaling loop during the
malignant
transformation of human breast epithelial cells. Cancer Research
64:7078-85
Pankonin MS,
Gallagher JT, Loeb JA. (2005) Specific
structural features of heparan sulfate proteoglycans potentiate
neuregulin-1 signaling.. J Biol Chem. 280(1):383-8.
Taveggia C,
Zanazzi G, Petrylak A, Yano H, Rosenbluth J, Einheber S, Xu X, Esper
RM, Loeb JA, Shrager P, Chao MV, Falls DL, Role L, Salzer JL. (2005) Neuregulin-1
type III determines the ensheathment fate of axons. .
Neuron. 47(5):681-94.
Rakhade SN, Yao
B, Ahmed S, Asano E, Beaumont TL, Shah AK, Draghici S, Krauss R,
Chugani HT, Sood S, Loeb JA.. (2005) A
common pattern of persistent gene activation in human neocortical
epileptic foci. Ann Neurol. 58(5):736-47.
Hapner SJ,
Nielsen KM, Chaverra M, Esper RM, Loeb JA, Lefcort F (2006) NT-3
and CNTF exert pleiotropic effects in the immature dorsal root ganglion
including neuregulin-mediated proliferation of progenitor cells and
neuronal differentiation. Dev. Biol. 297(1):182-97.
Esper RM,
Pankonin, MS, Loeb JA (2006) Neuregulins:
Versatile growth and differentiation factors in nervous system
development and human disease, Brain Res. Rev. , 51:161-75.
Loeb JA (2007) Neuroprotection
and repair by neurotrophic and gliotrophic factors in multiple sclerosis,
Neurology 68;38-42..
Rakhade SN, Shah AK, Agarwal R, Yao B, Asano E, and Loeb JA (2007) Activity-dependent Gene Expression Correlates with Interictal Spiking in Human Neocortical Epilepsy. Epilepsia 48 Suppl 5:86-95. Erratum in: Epilepsia. 2007 Dec;48(12):2380.
Rakhade SN and Loeb JA (2008) Regional
Down-regulation of Neuronal Glutamate Transporters at Human Neocortical
Epileptic Foci, Epilepsia, Feb;49(2):226-36. Epub 2007 Sep 12.
Pankonin MS, Kamholz J,
Sohi J and Loeb JA. (2009) Differential
Distribution of Neuregulin in Human Brain and Spinal Fluid Brain
Res, 1258, 1-11.
Esper RM and Loeb
JA. (2009) Neurotrophin
Activation of Protein Kinase C Delta Induces Neuregulin Release from
Neurons. J. Biol. Chem. Jul 31. [Epub ahead of print].
Ma Z, Li Q, An, H,
Pankonin MS, Loeb JA. (2009) Targeting
Her2 Signaling with Neuregulin's Heparin-Binding Domain J.
Biol. Chem. Aug 28. [Epub ahead of print].
Clinical
Neuroscience Publications:
Loeb JA (1998) Functional improvement in a patient with
basal ganglia
calcification using a bisphosphonate. Movement disorders
13:345-349.
Loeb JA (1998) Features
of Leao's spreading depression in patients with lesions near sensory
cortex.
J. Epilepsy 11:110-115.
Loeb JA (2002) Recertification for neurologists, (Post publication peer
review;
letter to the editor) Neurology (on-line).
Li J, Loeb
JA, Shy ME, Shah AK, Tselis AC, Kupski WJ, and Lewis RA
(2003) Asymmetric
flaccid paralysis: A neuromuscular presentation of West Nile virus
infection. Ann. Neurol. 53:703-10.
Nash
TE, Del Brutto OH, Butman JA, Corona T, Delgado-Escueta A, duron R,
Evans CAW,
Gilman RH, Gonzalez AE, Loeb JA, Medina MT, Pietch-Escueta S, Pretell
EJ,
Takayanagui OM, Theodore W, Tsang VCW, Garcia HH (2004) Calcific
neurocysticercosis and epileptogenesis. Neurology 62:
1934-38.
Maslinksi PG
an d Loeb JA (2004) Pica-Associated
Cerebral Edema in an Adult. J Neurol. Sci 225:149-151.
Loeb
JA, Sohrab SA, Huq M, Fuerst,
D (2006) Brain
calcifications induce neurological dysfunction that can be reversed by
a bone drug J. Neurol. Sci. 243:77-81.
TE.
Nash, G Singh, AC White, V
Rajshekhar, JA Loeb, JV Proaño, OM Takayanagui, AE
Gonzalez, JA Butman, C DeGiorgio, OH. Del Brutto, A Delgado-Escueta,
CAW Evans, RH Gilman, SM Martinez, MT Medina, J Pretell, J
Teale, HH. Garcia (2006) Treatment
of Neurocysticercosis - Current Status and Future Research Needs.
Neurology, 67(7):1120-7.
Shah AK, Agarwal R, Carhupoma JR, Loeb JA (2006) Compressed
EEG pattern analysis for critically ill neurological-neurosurgical
patients. Neurocritical Care 5(2):124-33.
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