Opportunities to participate in research projects in Molecular Medicine and Genetics are available as part of the Center for Molecular Medicine and Genetics SURP. Areas of study include, cell cycle regulation, chromosome structure and function, gene regulation, molecular neurobiology, differentiation and development, molecular biology of cancer, genetic engineering, genetics of cardiovascular diseases, computational biology, and molecular evolution
Leon Carlock, Molecular neurobiology; Huntington’s disease; neuron-specific gene expression; demyelinating disease.
Gerald Feldman, Use of molecular technologies in the diagnosis of genetic diseases; clinical genetics and dysmorphology; al programs in medical genetics residency training.
Russell L. Finley, Jr. Regulatory networks that control cell proliferation; cell cycle regulation during development; yeast technology.
Alexander Gow, Molecular pathogenesis of CNS diseases; molecular characterization of the claudin family of integral membrane tight junction proteins during development in brain, testes and inner ear using transgenic and homologous recombination in embryonic stem cells.
Lawrence I. Grossman, Molecular genetics and evolution of the electron transport chain; cytochrome c oxidase; mitochondria and mitochondrial diseases.
Henry H.Q. Heng, Molecular cytogenetics; high order structure of chromosomes; genome structure and function; genetic and physical mapping; genomic instability and cancer.
Maik Hüttemann, Function of cytochrome c oxidase isoforms, oxygen sensing, and role of mitochondria in cancer.
John Kamholz, Regulation of myelination; molecular pathophysiology of demyelinating disease.
Greg Kapatos, Cellular and molecular biology of monoamine neurotransmitter secreting neurons.
Stephen A. Krawetz, Gene therapy; control of development and differentiation; expression of connective tissue genes and genes controlling spermatogenesis; computer-assisted sequence analysis.
Markku Kurkinen, Extracellular matrix; metalloproteinases; gene regulation; development; disease.
Wayne Lancaster, Papillomaviruses: molecular biology, evolution, and role in human carcinogenesis; cancer cell genome instability; ovarian carcinogenesis.
Susan Land, Genomics and automated high through-put techniques such as microarrays, DNA sequencing and genotyping.
Leonard Lipovich
, The impact of primate-specific genes on phenotypes, pathways, and human health; Genomics, bioinformatics, long noncoding-RNA genes, and integrated functional analyses.
Li Li, Gene regulation during cardiovascular and hematopoietic development.
Jeffrey Loeb, Developmental neuroscience; molecular mechanisms in synapse formation; neuregulins and neurotrophins in synaptic development; functional genomic study of the pathogenesis of epilepsy.
Michael E. Shy, Molecular biology of Schwann cell axonal interactions; gene therapy in the peripheral nervous system.
Michael Tainsky, Inherited cancer and genomic instability; control of transcription in cancer cells; Li-Fraumeni familial cancer syndrome.
Angela Trepanier, Educational programs in human genetics and genetic counseling; cancer genetics.
Kezhong Zhang, Signaling pathways from the endoplasmic reticulum and mitochondria; unfolded protein response, oxidative stress and inflammation in health and disease.
Ren Zhang, Obesity and diabetes; the leptin signaling pathway and mechanisms of leptin resistance; comparative genomics.
